[PDF][PDF] Transient nodal signaling in left precursors coordinates opposed asymmetries shaping the heart loop

A Desgrange, JF Le Garrec, S Bernheim… - Developmental Cell, 2020 - cell.com
… Our results show that the generator of asymmetry is … the left-right patterning of the heart poles
correlates with the … in the right second heart field, as well as the asymmetric contribution of …

[HTML][HTML] Anterior lateral plate mesoderm gives rise to multiple tissues and requires tbx5a function in left-right asymmetry, migration dynamics, and cell specification of …

LMF Mao, EATB Anderson, RK Ho - Developmental biology, 2021 - Elsevier
asymmetrical contributions of lateral aLPM-derived heart … and arterial poles are called the
Second Heart Field (SHF). … unintended photoconversions did not contribute to the heart as …

The heart field transcriptional landscape at single-cell resolution

RG Kelly - Developmental Cell, 2023 - cell.com
… the second heart field (SHF), contribute progressively during looping morphogenesis to the
right ventricle and outflow tract at the arterial pole of the heartleft-right expression results from …

The second heart field: the first 20 years

K Zhao, Z Yang - Mammalian Genome, 2023 - Springer
… prominent anteriorposterior and leftright regionalization. The … of Hox contribute to the
venous pole of the heart and the Tbx1… the initiation of heart looping, but regulates the asymmetric

Shaping the mouse heart tube from the second heart field epithelium

P Palmquist-Gomes, SM Meilhac - Current Opinion in Genetics & …, 2022 - Elsevier
… Finally, the poles of the heart undergo asymmetric movements … These processes altogether
contribute to the left-rightresults in unexpected left/right contributions to both poles of …

Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping

T Holm Bonnelykke, MA Chabry, E Perthame… - bioRxiv, 2024 - biorxiv.org
… syndrome, its contribution to asymmetric organogenesis is … asymmetric gene, but also a
novel player in the left-right 137 … morphological asymmetry at the arterial pole of the 150 heart

[HTML][HTML] Outflow tract formation—embryonic origins of conotruncal congenital heart disease

S Stefanovic, HC Etchevers, S Zaffran - Journal of Cardiovascular …, 2021 - mdpi.com
… and her contributions to the field of cardiac development and … heart is less surprising in light
of its substantial contributions to … cells of the pSHF contribute to both poles of the heart tube. …

Heart development and congenital structural heart defects

L Houyel, SM Meilhac - Annual review of genomics and human …, 2021 - annualreviews.org
… ) enable the contributions of the left/right second heart field to be … the arterial and venous
poles of the heart is consistent with … the facts that left/right asymmetry is regulated independently …

[HTML][HTML] The Tbx20-TLE interaction is essential for the maintenance of the second heart field

W Edwards, OK Bussey, FL Conlon - Development, 2023 - journals.biologists.com
cardiac progenitor development and function contribute to … to the anterior and posterior
poles of the developing heart tube … Unexpectedly, we also observed a drastic increase in the …

[HTML][HTML] Drosophila as a Model to Understand Second Heart Field Development

C Bileckyj, B Blotz, RM Cripps - Journal of Cardiovascular Development …, 2023 - mdpi.com
… Here, we review the prior contributions of the Drosophila … second heart field cells contribute
to the poles of the elongating … a pivotal role in cardiac leftright asymmetrical morphogenesis […